摘要：Background: Lichen sclerosus most commonly affects the genital area. Contrarily to lichen planus, the involvementof the oral or vaginal mucosa is rare. Only four cases of vaginal lichen sclerosus have been described in theliterature.Case report: The authors report two cases of postmenopausal women with a history of vulvar pruritus and burning.Both presented with lesions of the vaginal mucosa compatible with lichen sclerosus, and genital prolapse. Vaginalbiopsies confirmed the diagnosis. Initial treatment with topical clobetasol was effective in one of the patients,but in the other patient line therapy with pimecrolimus, triamcinolone, and retinoids was needed.Conclusion: Vaginal lichen sclerosus may be underdiagnosed and genital prolapse may favour the development ofvaginal lesions.
