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  • 标题:Immunoadjuvant effect of garlic ( Allium sativum )–mineral oil suspension on immunity and resistance to Aeromonas hydrophila infection in rohu, Labeo rohita
  • 作者:Pujarini Dash ; Swati Yadav ; P. K. Sahoo
  • 期刊名称:International Aquatic Research
  • 印刷版ISSN:2008-6970
  • 出版年度:2014
  • 卷号:6
  • 期号:3
  • 页码:167-173
  • DOI:10.1007/s40071-014-0072-8
  • 语种:English
  • 出版社:BioMed Central
  • 摘要:The immunomodulatory effect of garlic–mineral oil as a modified adjuvant was investigated in rohu, Labeo rohita along with formalin-killed Aeromonas hydrophila . The garlic extract was not having any proteolytic effect on the tested antigen as marked in SDS-PAGE. The efficacy of graded levels of modified adjuvant formulation was assessed by measuring serum hemolysin and agglutination titers as well as level of protection against A. hydrophila challenge in the immunized fish at days 10 and 30 post-vaccination (dpv). The higher hemolysin and bacterial agglutinin titers along with significantly lower mortality against A. hydrophila challenge in modified adjuvant-based vaccinated fish, particularly at low level of garlic incorporation, indicated the pronounced immunoadjuvant role of this modified adjuvant formulation in rohu.
  • 关键词:Adjuvant ; Allium sativum ; Aeromonas hydrophila ; Labeo rohita
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