摘要：The effects of regular exercise on physical functioning and health-related quality of life (HRQOL) have been thoroughly studied. In contrast, little is known about the changes which occur following cessation of activity (detraining). Here, we have investigated the effect of a 3 month detraining period on HRQOL and on handgrip strength in elderly people who had regularly exercised, and examined the association of these variables with falls. Thirty-eight women and 11 men (mean age, 75.5±5.7 years) took part in a supervised physical exercise program for 9 months, followed by a 3 month detraining period. Participants completed the SF-36 HRQOL questionnaire at the beginning of detraining (baseline) and 3 months later. Handgrip strength and number of falls were also recorded. Participants had been exercising for 12.1±8.7 years. After the detraining period, we found a significant (p < 0.001–-0.05) decline in all SF-36 dimensions, with the exception of handgrip strength. Women presented a larger decline (p < 0.05) in more items than men. During the detraining period, 18.4% participants had a fall incident. HRQOL declined in both fallers and non-fallers during detraining. Interestingly, fallers already had at baseline significantly lower values in physical functioning (p < 0.05), emotional role (p < 0.05) and mental health (p < 0.01), than non-fallers. An important decline was found in most items of the SF-36 following a 3 month detraining period, particularly in women. In contrast, strength of the upper limb was not affected by the detraining. The prior lower HRQOL values of those who will subsequently fall suggest that this criterion should be studied as a candidate risk factor for falls. Efforts should be made to encourage the elderly to continue with exercise activities and/or to shorten holiday break periods, in order to maintain their quality of life. The protocol was registered as a clinical trial in the ANZCTR (trial ID: ACTRN12617000716369 ).
关键词：Quality of life ; Elderly ; Supervised physical activity ; Fall
