出版社：Indian Association of Preventive and Social Medicine Uttar Pradesh and Uttarakhand Chapter
摘要：Background: Safe blood is a critical component in improving health care and in preventing the spread of infectious disease. But the quality and safety of blood transfusion is still a concern for health-care personnel’s. We analyzed the sero-prevalence and changing trends of transfusion transmitted infections (TTIs) among blood donors in a tertiary care hospital. Objectives: This retrospective study aimed to analyze the percentage of voluntary and replacement blood donors and to know the sero-prevalence and changing trends of TTIs among blood donors in a tertiary care hospital. Methods: Blood donations collected over a 6-year period were studied for the type of donation (voluntary or replacement), number of seroreactive cases. Samples were screened for anti HIV 1 & 2, HBsAg, anti HCV, syphilis and malaria. All reactive samples were retested before being labeled as seropositive. Results: Of the 187575 donors, 134391 (71.6%) were replacement and 53184 (28.4%) voluntary donors .Of all the blood donors there were 8577 (4.57%) seroreactive cases which included 492 (0.26%) of anti HIV 1&2 , 1937 (1.03%) of HBsAg, 2867 (1.53%) of anti HCV, 3270 (1.74%) of syphilis and 11 (0.006%) of malaria. The overall seropositivity for various TTIs are more in replacement donor i.e. (3.8%), where as it was only (0.7%) among voluntary blood donors and this was statistically significant (p<0.05). Conclusion: Voluntary donations are safer as compared with replacement ones and need to be encouraged. The screening of blood donors is the corner stone in assuring the safety of blood transfusion.
其他摘要：Background: Safe blood is a critical component in improving health care and in preventing the spread of infectious disease. But the quality and safety of blood transfusion is still a concern for health-care personnel’s. We analyzed the sero-prevalence and changing trends of transfusion transmitted infections (TTIs) among blood donors in a tertiary care hospital. Objectives: This retrospective study aimed to analyze the percentage of voluntary and replacement blood donors and to know the sero-prevalence and changing trends of TTIs among blood donors in a tertiary care hospital. Methods: Blood donations collected over a 6-year period were studied for the type of donation (voluntary or replacement), number of seroreactive cases. Samples were screened for anti HIV 1 & 2, HBsAg, anti HCV, syphilis and malaria. All reactive samples were retested before being labeled as seropositive. Results: Of the 187575 donors, 134391 (71.6%) were replacement and 53184 (28.4%) voluntary donors .Of all the blood donors there were 8577 (4.57%) seroreactive cases which included 492 (0.26%) of anti HIV 1&2 , 1937 (1.03%) of HBsAg, 2867 (1.53%) of anti HCV, 3270 (1.74%) of syphilis and 11 (0.006%) of malaria. The overall seropositivity for various TTIs are more in replacement donor i.e. (3.8%), where as it was only (0.7%) among voluntary blood donors and this was statistically significant (p<0.05). Conclusion: Voluntary donations are safer as compared with replacement ones and need to be encouraged. The screening of blood donors is the corner stone in assuring the safety of blood transfusion.
Loading...
