To demonstrate longitudinal refractive changes of anisometropia children.

This retrospective study included patients (or children) with anisometropia ≥ 1 diopters (D) for 5 years who visited our hospital between January 2013 and December 2014 with patients having annual refraction test data from 5-years-old to 10-years-old.

A total of 37 children satisfied the inclusion criteria. Twenty-one children had hyperopic anisometropia and 16 children had myopic anisometropia. All hyperopic anisometropia and 12 myopic anisometropia children who had unilateral amblyopia were treated with occlusion therapy. The mean anisometropia at 5 years of age was 3.02 D and in the 37 children, the final degree of anisometropia was not significantly different between the 5-year-old and 10-year-old patients. In the high anisometropia and low anisometropia groups and in the myopia and hyperopia groups, the final degree of anisometropia was not significantly different at 5 years of age versus 10 years of age.

In patients with anisometropia, spherical equivalent values did not show a significant difference when comparing 5-year-old versus 10-year-old patients and changes in the spherical equivalent values of eyes from both groups progressed to the same degree even if there was anisometropia in myopic and hyperopic patients.