期刊名称：International Journal of Innovative Research in Science, Engineering and Technology
印刷版ISSN：2347-6710
电子版ISSN：2319-8753
出版年度：2017
卷号：6
期号：5
页码：8227
DOI：10.15680/IJIRSET.2017.0605162
出版社：S&S Publications
摘要：Diabetes Mellitus (DM) is a metabolic disease characterized with persistent hyperglycemia due to ,inappropriate glucose use or insufficient insulin production of pancreas. There is a defect in insulin effect, secretion orboth. Due to sedentary life style and obesity, incidence of type 2 diabetes mellitus is increasing. Oral hypoglycaemicdrugs or insulin therapy along with diet control and exercise helps the diabetic individual to keep proper glycemiccontrol. Glycemic control is must in DM. Glycemic control is the main target of treatment in protection against organdamage and other complications of DM. Glycatedhemoglobin (HbA1C) follow-up is made in order to measure theefficiency of the treatment in DM and observe the glycemic control. HbA1C is formed as the result of non-enzymaticreaction of glucose to hemoglobin. It provides information on the average blood glucose levels of past 8-12 weeks inDM treatment. HbA1C is the golden standard in glycemic control of patients. Hyperglycemia tend to have effect onRBC survival and glycation of haemoglobin Red blood cell distribution width (RDW) is the symbol of red blood cellvolume distribution width coefficient of variation. It may be considered as heterogeneity index and is the equivalent ofanisocytosis observed in peripheral blood smear.The present study was undertaken to explore the correlation betweenRDW and HbA1c in diabetic individuals presented at Laboratroty, Ruby Hall Clinic, Pune. The results of study willhelp to determine the risk of future cardiovascular disease and organ damage due to hyperglycemia.
关键词：Red Cell Distribution Width; Glycosylated Hemoglobin; GlycatedHemoglobin; Coronary Artery;Disease; Cardiovascular Disease; Diabetes Mellitus; American Diabetes Association
