出版社:The International Institute for Science, Technology and Education (IISTE)
摘要:Abstract Aim of the study is to determined G-protein coupled receptor levels in diabetic and diabetic nephropathy patients and compare the results with control group. Study also, aimed to find relationship of GPCR with HbA1c , cholesterol and Triglyceride in these patients ,in order to that GPCR could be used as a marker combat diabetes and its complication . One hundred fifty subjects were involved in this study that divided into three groups as follows:- Control group (G1) consists of 50 healthy individuals. Diabetic group (G2) consists of 50 patients and diabetic Nephropathy group (G3) consists of 50 patients . levels of HbA1c % , urea , createnine , albumin , TC, TG, HDL-c, LDL-c , VLDL-c and GPCR were determined in all subjects. Conclusion could be drawn from study that the difference between GPCR levels among groups indicate GPCR may be used as a marker in development of diabetic nephropathy as well as their are a significant relation for GPCR with TC and TG . Keywords: GPCR , diabetic and diabetic nephropathy