摘要:Chitosan grafted with acrylonitrile loaded silver nanocomposite coated alginate beads were successfully prepared first, alginate beads were synthesized with homogenous structures sized ranging from 1.5 to 2 mm. The alginate beads were then submitted to surface modification (coating) using the nanocomposite. The presence of nanocomposite along with the structure of materials were characterized by making use of FT-IR, XPS, EDX-SEM, TEM, UV-vis spectrophotometer. The nanocomposite treated samples were tested for their antibacterial activity against Escherichia coli ( E. coli ) as gram negative bacteria and Staphylococcus aureus ( Staph. aureus ) as gram positive strain. The antibacterial activity was examined by both zone of inhibition and turbidmetery test method. Biological results indicate that the newly synthesized materials have excellent antibacterial performance against all types of microbes.