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  • 标题:Alkylated Benzoquinones: Ardisiaquinones A–H from the Leaves of Ardisia quinquegona and Their Anti-Leishmania Activity
  • 本地全文:下载
  • 作者:Shintaro Asaumi ; Susumu Kawakami ; Sachiko Sugimoto
  • 期刊名称:Chemical and Pharmaceutical Bulletin
  • 印刷版ISSN:0009-2363
  • 电子版ISSN:1347-5223
  • 出版年度:2018
  • 卷号:66
  • 期号:7
  • 页码:757-763
  • DOI:10.1248/cpb.c18-00281
  • 语种:English
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Eight alkylated benzoquinone derivatives, named ardisiaquinones A–H, were isolated together with four known compounds from the leaves of Ardisia quinquegona using a combination of different chromatography techniques. Their structures were elucidated by spectroscopy and by the preparation of methyl ethers. Anti- Leishmania activity and cytotoxicity of the isolated compounds were assayed. Some compounds showed moderate anti- Leishmania activity, however, always associated with cytotoxicity.
  • 关键词:Ardisia quinquegona;Primulaceae;alkylated benzoquinone;anti-Leishmania activity
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