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  • 标题:Hypersensitivity Pneumonitis Associated with Environmental Mycobacteria
  • 作者:William Beckett ; Michael Kallay ; Akshay Sood
  • 期刊名称:Environmental Health Perspectives
  • 印刷版ISSN:0091-6765
  • 电子版ISSN:1552-9924
  • 出版年度:2005
  • 卷号:113
  • 期号:6
  • 页码:767-770
  • DOI:10.1289/ehp.7727
  • 语种:English
  • 出版社:OCR Subscription Services Inc
  • 摘要:A previously healthy man working as a machine operator in an automotive factory developed respiratory symptoms. Medical evaluation showed abnormal pulmonary function tests, a lung biopsy showed hypersensitivity pneumonitis, and his illness was traced to his work environment. His physician asked the employer to remove him from exposure to metalworking fluids. Symptoms reoccurred when he was later reexposed to metalworking fluids, and further permanent decrement in his lung function occurred. Investigation of his workplace showed that five of six large reservoirs of metalworking fluids (cutting oils) grew Mycobacterium chelonae (or Mycobacterium immunogenum ), an organism previously associated with outbreaks of hypersensitivity pneumonitis in automaking factories. His lung function remained stable after complete removal from exposure. The employer, metalworking fluid supplier, union, and the National Institute for Occupational Safety and Health were notified of this sentinel health event. No further cases have been documented in this workplace.
  • 关键词:atypical mycobacteria; extrinsic allergic alveolitis; hot tub; hypersensitivity pneumonitis; metalworking fluids; Mycobacterium chelonae ; Mycobacterium immunogenum ; nontuberculous mycobacteria; occupational lung disease
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