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  • 标题:A dichotomy in the lipophilicity of natural estrogens, xenoestrogens, and phytoestrogens.
  • 作者:A R Cunningham ; G Klopman ; H S Rosenkranz
  • 期刊名称:Environmental Health Perspectives
  • 印刷版ISSN:0091-6765
  • 电子版ISSN:1552-9924
  • 出版年度:1997
  • 卷号:105
  • 期号:Suppl 3
  • 页码:665-668
  • 语种:English
  • 出版社:OCR Subscription Services Inc
  • 摘要:Using two independent analyses, it is demonstrated that natural (e.g., estradiol) and some xenoestrogens (e.g., methoxychlor metabolite) are characterized by a lipophilic region that is absent in nonestrogens as well as in phytoestrogens. It is suggested that this lipophilic region affects binding to specific receptors and may, in fact, differentiate harmful from beneficial estrogens. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (874K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 665 666 667 668
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