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  • 标题:Thyroid-stimulating hormone levels in children from Chernobyl.
  • 作者:M R Quastel ; J R Goldsmith ; L Mirkin
  • 期刊名称:Environmental Health Perspectives
  • 印刷版ISSN:0091-6765
  • 电子版ISSN:1552-9924
  • 出版年度:1997
  • 卷号:105
  • 期号:Suppl 6
  • 页码:1497-1498
  • 语种:English
  • 出版社:OCR Subscription Services Inc
  • 摘要:This study assesses parameters of thyroid function in persons who resided in Ukraine, Belarus, and southern Russia and exposed at 0 to 16 years of age to radioiodine contamination from the Chernobyl accident. Six to eight years after the accident a group of 300 young people who had immigrated to Israel were interviewed, underwent physical and ultrasound thyroid examination, and had their serum tested for thyroid-stimulating hormones (TSH), thyroid hormones, thyroglobulin, and antithyroid antibodies. Comparative groups came from areas with high (>1 Ci/km2) or low (< 1 Ci/km2) 137Cs ground contamination. Girls from high contamination areas, when compared to girls from areas with low ground contamination, showed significant upward shifts in levels of serum TSH (p = 0.023) although remaining within normal limits. Boys showed no significant differences. There was no evidence for differences in thyroid size or nodularity between the two groups of girls. A working hypothesis is proposed by which the shift in TSH levels in girls from high radiocontamination areas was associated with subclinical radiation damage from environmental radioiodine at the time of the accident. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (447K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 1497 1498
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