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  • 标题:The effect of gamma-irradiation on the adherent capacity and iron metabolism of alveolar macrophages in mice and rats.
  • 作者:Y Kubota ; H Sato ; S Takahashi
  • 期刊名称:Environmental Health Perspectives
  • 印刷版ISSN:0091-6765
  • 电子版ISSN:1552-9924
  • 出版年度:1992
  • 卷号:97
  • 页码:163
  • 语种:English
  • 出版社:OCR Subscription Services Inc
  • 摘要:The effect of external gamma-irradiation on the survival of alveolar macrophages (AM) and on the extracellular release of 59Fe from AM-ingested [59Fe]iron hydroxide colloid was investigated in vitro using cells from C3H mice and Wistar rats. 59Fe release from mouse AM was enhanced by irradiation in a dose-dependent fashion, but irradiation up to 112 Gy did not affect the release from rat AM. Cell survival of AM, measured by direct counting of cell nuclei of adherent AM or vital staining with crystal violet, decreased dose dependently in mice and rats, but mouse AM were more radiosensitive than rat AM. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (303K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 163 164 165
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