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  • 标题:Induction of SOS functions in Escherichia coli and biosynthesis of nitrosamine in rabbits by nitrogen dioxide.
  • 作者:H Kosaka ; M Uozumi ; T Nakajima
  • 期刊名称:Environmental Health Perspectives
  • 印刷版ISSN:0091-6765
  • 电子版ISSN:1552-9924
  • 出版年度:1987
  • 卷号:73
  • 页码:153
  • 语种:English
  • 出版社:OCR Subscription Services Inc
  • 摘要:Nitrogen dioxide induced SOS functions in Salmonella typhimurium and Escherichia coli K-12 and was mutagenic in Escherichia coli WP2. When a rabbit was administered aminopyrine intravenously and administered nitrogen dioxide by inhalation, N-nitrosodimethylamine was detected in its blood. Analysis was conducted with 15N-nitrosodimethylamine as an internal standard by a combination of capillary gas chromatography and mass spectrometry. Accompanying administration of cystamine increased the blood concentration of N-nitrosodimethylamine in the rabbit, suggesting inhibition of its metabolism. Concurrent sulfur trioxide inhalation increased N-nitrosodimethylamine formation in the rabbit. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (634K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 153 154 155 156
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