摘要:Examples of a combined approach using in vivo as well as in vitro methods for the assessment of prenatal toxicity are presented. The topics discussed include the analysis of the possible embryotoxic potential of valproic acid (VPA), female sex hormones, bis(tri- n -butyltin) oxide (TBTO), and acyclovir and the problem of supplementing in vitro systems with drug-metabolizing activity. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (5.5M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103