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  • 标题:Methods and approaches for assessing immunotoxicity: an overview.
  • 作者:J H Dean ; M I Luster ; G A Boorman
  • 期刊名称:Environmental Health Perspectives
  • 印刷版ISSN:0091-6765
  • 电子版ISSN:1552-9924
  • 出版年度:1982
  • 卷号:43
  • 页码:27
  • 语种:English
  • 出版社:OCR Subscription Services Inc
  • 摘要:The goals of the National Toxicology Program as they relate to immunological evaluation in toxicity assessment are discussed. The advantages of immune function assays for defining cellular injury as subtoxic levels following exposure to general or immunocyte specific chemical toxicants are proposed. A comprehensive screening panel of immune function and host resistance assays is presented in the context of an NIEHS approach for immunotoxicity assessment and methods selection. A second panel for defining the mechanism underlying immunological injury was also described. Studies utilizing these methods and approaches are described in companion papers by our group. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (404K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 27 28 29
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