摘要:The isolated perfused lung (IPL), when compared to available in vitro and in vivo pulmonary systems, is a preparation that fulfills a majority of the ideal criteria for studying metabolism, binding and/or physiological response to xenobiotics. The IPL is an exceptionally useful method when there is a need for concurrent administration of multiple agents in different physical forms. Various details such as physiological and biochemical parameters and the construction of a small animal tracheal valve system are discussed. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (552K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 67 68 69 70 71