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  • 标题:Children with melioidosis in Far North Queensland are commonly bacteraemic and have a high case fatality rate
  • 本地全文:下载
  • 作者:Simon Smith ; James D. Stewart ; Catherine Tacon
  • 期刊名称:Communicable Diseases Intelligence
  • 印刷版ISSN:1447-4514
  • 电子版ISSN:1445-4866
  • 出版年度:2017
  • 卷号:41
  • 期号:4
  • 页码:E318
  • 出版社:Government Department of Health and Ageing
  • 摘要:Paediatric melioidosis is uncommon in Northern Australia. In the Northern Territory, children withmelioidosis often report an inoculation event and localised skin and soft tissue infections predominate.However, in Far North Queensland, children with melioidosis are frequently bacteraemic andhave a high case fatality rate. To confirm this observation, all culture-confirmed cases of Burkholderiapseudomallei processed at Cairns Hospital between 1998 and March 2017 were reviewed. During thestudy period, B. pseudomallei was isolated from 223 people; ten (4%) were children (aged from threedays to 14 years). Bacteraemia occurred in 6/10 (60%) children compared with 161/213 (76%) adults(p=0.24). The primary diagnosis was localised, cutaneous disease in three children, meningoencephalitisin two and pneumonia in two. Three had bacteraemia with no primary source evident. No childhad a parotid abscess or liver abscess. Five children (50%) died, and all of whom were bacteraemic.
  • 关键词:Tropical medicine; melioidosis; paediatrics
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