文章基本信息
- 标题：Anti-pseudomonal Effect of a Nephrite-containing Contact Lens Storage Case
- 本地全文：下载
- 作者：Lee, Sang Min ; Jung, Jae Woo ; Lee, Dong Hyun 等
- 期刊名称：Journal of the Korean Ophthalmological Society
- 印刷版ISSN：0378-6471
- 出版年度：2018
- 卷号：59
- 期号：8
- 页码：724-729
- DOI：10.3341/jkos.2018.59.8.724
- 语种：Korean
- 出版社：The Korean Ophthalmological Society
- 摘要：Purpose
To compare the anti-pseudomonal effect of nephrite-containing contact lens (CL) storage cases with conventional CL storage cases.
MethodsThe degree of proliferation and adhesion of Pseudomonas aeruginosa ( P. aeruginosa ) on 1st–3rd generation silicone hydrogel contact lenses (SHCLs) was compared by using both 5% nephrite-containing CL storage cases and conventional CL storage cases. The degree of adhesion of P. aeruginosa to the CL was also compared in 1% or 5% nephrite solution and multipurpose solution (MPS).
ResultsNephrite-containing CL storage cases showed a significant inhibitory effect on P. aeruginosa proliferation ( p = 0.03) and significantly reduced the number of adherent P. aeruginosa on all 1st–3rd generation SHCLs compared with conventional CL storage cases ( p = 0.02, p = 0.03, and p < 0.01, respectively). There was no significant anti-pseudomonal effect of 1% and 5% nephrite solutions compared with MPS.
ConclusionsNephrite may be the next generation substance that reduces infectious keratitis caused by P. aeruginosa when added to CL storage cases.
- 关键词：Contact lens storage case; Infectious keratitis; Multipurpose solution; Nephrite; Pseudomonas aeruginosa
