摘要:Three new compounds, sydowianumols A ( 1 ), B ( 2 ), and C ( 3 ), were isolated from culture broth and mycelial extracts of Poculum pseudosydowianum (TNS-F-57853), an endophytic fungus isolated from fresh leaves of Quercus crispula . The structures of new compounds 1 – 3 were elucidated from spectroscopic data. Sydowianumols A ( 1 ) and B ( 2 ) exhibited antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) with 90% minimum inhibitory concentration (MIC90) values of 12.5 µg/mL.