摘要："Objectives: The study was un-dertaken to evaluate maternal and Perinatal outcomes follow-ing transcervical intrapartum amnioinfusion in women with moderate to thick meconium stained amniotic fluid. Methods: A randomized control study was conducted on 200 women with moderate to thick meconium stained amniotic flu-id during labor. Group A (study group) of 100 cases received am-nioinfusion. Group B (control group) of 100 cases received standard obstetric care. Fetal heart rate monitoring was done using cardiotocography. The details regarding mode of deliv-ery, Apgar score, Perinatal and maternal complications were noted. Results: 66% of women were in the age group of 21-25 years. Av-erage cervical dilatation at detec-tion of meconium and detection of meconium to delivery interval was similar in both groups. In the study group, 68% women had normal vaginal delivery as compared to 49% in the control group (p<0.01). Operative deliv-ery was required in 32% and 51% cases in groups A and B respectively. Meconium aspira-tion syndrome was developed in 5% cases in group A and 15% cases in group B, which was significant (p=0.02, Odds ratio 0.29 (0.1-0.85)). There were no significant differences in Apgar scores, NICU admissions and Perinatal mortality between two groups. No any maternal com-plications were noted due to amnioinfusion. Conclusion: Intrapartum amnio-infusion in meconium stained amniotic fluid is simple, safe and inexpensive intervention to reduce the rates of meconium aspiration syndrome and its complications."
关键词：Intrapartum amnioinfusion; me-conium stained amniotic fluid; meconium aspiration syndrome; randomized control study
