摘要：Background: A fixed effects meta-analysis of ten exercise training in trials heart failure patients was conducted. The aim of this current work was to compare different approaches to meta-analysis using the same dataset from the previous work on ten exercise training trials in heart failure patients.Methods: The following different meta-analysis techniques were used to analyse the data and compared the effects of exercise training on BNP, NT-pro-BNP and peak VO2 before and after exercise training:(1) Trial level (traditional) level MAi) Follow up (post-exercise training intervention) outcome only.ii) Baseline-follow up difference(2) Patient level MA by Post-Stage ANCOVAi) naive model does not take into account trial levelii) Single Stageiii) Two Stage(3) Post outcome onlyi) Single stageii) Pre-post outcome difference Single stage
