摘要:In Sri Lanka, Anopheles nigerrimus is resistant to a range of organophosphate and carbamate insecticides at both the larval and adult stages. Biochemical studies indicate that an alteration in acetylcholinesterase is the basis of resistance rather than increased metabolic breakdown of the insecticides. In contrast, A. culicifacies is resistant only to malathion and closely related compounds containing a carboxylate ester bond. Agricultural pesticides are the sole source of selection pressure for resistance in A. nigerrimus , while in A. culicifacies pressure arises predominantly from antimalarial spraying. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (938K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 753 754 755 756 757 758