摘要:Clinically important side-effects of primaquine are reviewed. These include gastrointestinal disturbances, methaemoglobinaemia, acute intravascular haemolysis in individuals deficient in glucose-6-phosphate dehydrogenase (G6PD), and possibly immunosuppression through inhibition of lymphocyte proliferation. Dosages of 30 or 45 mg (base) of primaquine, given at weekly intervals, are suitable for patients with G6PD deficiency. If possible, primaquine should not be administered until the acute symptoms of the malaria attack have been brought under control. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (693K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 391 392 393 394 395