摘要：Malarial antibody levels were measured by the enzyme-linked immunosorbent assay (ELISA) in two West African populations, one exposed to intense malaria transmission and the other protected. The results reflected the transmission of maternal antibody and, in the unprotected population, the subsequent increase of the ELISA values with age reflected the development of the immune response to malaria. Malaria control activities reduced ELISA values in the protected population. The limitations of the ELISA test used in this study are shown by the fact that numerous infants with previous proven parasitaemia were ELISA-negative. Purified antigens are needed to improve the ELISA test for use in serological surveys of malaria. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (858K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 429 430 431 432 433 434 435 436 437 438
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