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  • 标题:The effect of undernutrition on immunological responses to BCG and TAB vaccines in mice maintained on a natural diet
  • 作者:R. B. Narayanan ; Indira Nath ; U. N. Bhuyan
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1978
  • 卷号:56
  • 期号:5
  • 页码:781-786
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:A study was made on the effect of undernutrition on the immunological responses of mice to TAB and BCG vaccines. The mice were fed a diet comprising chapati and germinated grams; one group was fed ad libitum while another was given half the quantity consumed by the first group. The undernourished mice showed a poor immune response to BCG: only 23% showed a positive reaction to foot pad challenge with purified protein derivative, compared with 76% of the well-fed mice. The mean increase in thickness of the foot pad was also significantly smaller in the undernourished mice. Antibody titres against the H and O antigens of TAB were essentially similar in both groups of mice. The results suggest that undernutrition depresses cell-mediated immune responses but not humoral responses. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.0M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 781 782 783 785 786
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