摘要:A controlled field trial of a modified vaccine containing Salmonella typhi , TY 2 strain, in a dose of 400 × 109 killed organisms per capsule, was carried out in schoolchildren aged 6-17 years. The children were followed up for 6-8 months. There were 66 cases of typhoid fever in the vaccine group (7312 children) and 54 in the control group (7292 children who had received a placebo). This difference is not statistically significant. The results confirm that, as found in earlier trials, oral typhoid vaccine, in the dosages used so far, gives no protection. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (287K), or click on a page image below to browse page by page. 643 644