摘要:Relatively few cofactors have so far been demonstrated to be essential for the intracellular development of erythrocytic stages of malarial parasites. Besides 4-aminobenzoic acid, presumably required for the synthesis of folates, these are biotin and pantothenate. The pantothenate is not used directly by the parasites but rather as coenzyme A synthesized by the host erythrocyte. Parasites maintained extracellularly in vitro also have a requirement for exogenous adenosine triphosphate. No information is available concerning cofactor requirements of the sporogonic or pre-erythrocytic stages. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (552K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 285 286 287 288 289