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  • 标题:Cofactors and vitamins in the metabolism of malarial parasites. Factors other than folates
  • 作者:William Trager
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1977
  • 卷号:55
  • 期号:2-3
  • 页码:285-289
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:Relatively few cofactors have so far been demonstrated to be essential for the intracellular development of erythrocytic stages of malarial parasites. Besides 4-aminobenzoic acid, presumably required for the synthesis of folates, these are biotin and pantothenate. The pantothenate is not used directly by the parasites but rather as coenzyme A synthesized by the host erythrocyte. Parasites maintained extracellularly in vitro also have a requirement for exogenous adenosine triphosphate. No information is available concerning cofactor requirements of the sporogonic or pre-erythrocytic stages. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (552K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 285 286 287 288 289
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