摘要：A method is described of estimating the malaria incidence rate ĥ and the recovery rate r from longitudinal data. The method is based on the assumption that the phenomenon of patent parasitaemia can be represented by a reversible two-state catalytic model; it is applicable to all problems that can be represented by such a model. The method was applied to data on falciparum malaria from the West African savanna and the findings suggested that immunity increases the rate of recovery from patent parasitaemia by a factor of up to 10, and also reduces the number of episodes of patent parasitaemia resulting from one inoculation. Under the effect of propoxur, ĥ varies with the estimated man-biting rate of the vector while r ̂ increases, possibly owing to reduced super-infection. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (853K), or click on a page image below to browse page by page. 685 686 687 688 689 690 691 692 693
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