摘要：Both recovery and death of mice following acute infections with lymphocytic choriomeningitis virus appear to be mediated by a population of virus-specific thymus-derived (T) effector lymphocytes that possess lytic activity in vitro against virus-infected syngeneic fibroblasts. Whether recovery or death occurs is determined by the balance between two interdependent factors: (1) the extent of virus-induced modifications in the surfaces of cells comprising “target” tissues, and (2) the efficiency of the immune inductive process leading to the generation of effector T lymphocytes that recognize and destroy these modified cells. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (888K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 465 466 467 468 469 470
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