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  • 标题:Mechanisms of acquired immunity and epidemiological patterns of antibody responses in malaria in man
  • 作者:I. A. McGregor
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1974
  • 卷号:50
  • 期号:3-4
  • 页码:259-266
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:This paper considers the participation of macrophages, thymus-dependent lymphocytes (T-cells), and thymus-independent lymphocytes (B-cells) in man's immune response to malaria. Although phagocytosis by macrophages is an important feature of malaria the full extent of cooperation between these cells and T- and B-cells is not known. Evidence that T-cells play an important defensive role is at present unconvincing. B-cells on the other hand function importantly in the synthesis of immunoglobulins and specific antibodies and factors possibly influencing their activity are considered. Different epidemiological patterns of malaria antibodies in sera are described and the need for the routine inclusion of reliable antibody detection tests as part of malaria survey techniques, particularly where antimalarial drug usage is frequent, is emphasized. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.2M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 259 260 261 262 263 264 265 266
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