摘要:Cultivation of E strain of Rickettsia prowazeki in mouse lung resulted in a marked increase in virulence for guinea pigs following 12 passages (but not 6 passages) in both immunosuppressed and normal mice. Attempts at passaging E strain in normal guinea pigs were unsuccessful. Isolates of E strain in the chicken embryo yolk sac either from testes and peritoneal washings or from the brain of immunosuppressed guinea pigs did not show enhanced virulence for guinea pigs. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.1M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 257 258 259 260 261 262 263 264 265