摘要:Different DPT + typhoid vaccines were produced by two laboratories and tested in the field for untoward local or systemic reactions and in the laboratory for immunogenic properties. The combined DPT and acetone-inactivated and dried typhoid antigen was found to cause more numerous and more severe local and systemic reactions than the DPT and DPT + typhoid (heat—thiomersal) vaccines. The antibody responses to all four antigens in both of the combined DPT + typhoid vaccines were very satisfactory. From the results of these studies it is concluded that quadruple DPT + typhoid vaccine is suitable for use in areas where typhoid fever is a problem and where logistic and other considerations require the use of combined vaccines. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (710K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 47 48 49 50 51 52