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  • 标题:Mode of action of pyrethroids
  • 本地全文:下载
  • 作者:T. Narahashi
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1971
  • 卷号:44
  • 期号:1-2-3
  • 页码:337-345
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:Since pyrethroids are potent neuropoisons, their mechanism of action on the nervous system can best be studied by means of electrophysiological techniques. The nerve excitation occurs as a result of changes in nerve membrane permeabilities to sodium and potassium ions, and therefore any effect of pyrethroids can be interpreted in terms of such permeabilities. Detailed analyses of the action of allethrin on the giant axons of the cockroach, the crayfish, and the squid performed by means of intracellular microelectrode and voltage clamp methods have revealed the ionic basis of the action of allethrin on the nerve. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.0M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 337 338 339 340 341 342 343 344 345
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