摘要:The authors describe a simple test (the blood incubation infectivity test) by which Trypanosoma brucei (sensu stricto) may be differentiated from T. rhodesiense without recourse to human volunteers. The method consists in incubating the strain of trypanosome under test for 5 hours at 37°C in vitro in human blood, followed by observation of the effect of this procedure on the strain's infectivity to rats. Thirteen strains of T. rhodesiense were investigated; in each, the ability to infect rats was retained after incubation. In all 6 strains of man-tested T. brucei, it was destroyed. The consistency of the results with proven strains suggests very strongly that the blood incubation infectivity test provides a valid means of differentiating these parasites. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (577K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 911 912 913 914 915 916