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  • 标题:Duration of allergy and immunity in BCG-vaccinated guinea-pigs: A five-year study*
  • 本地全文:下载
  • 作者:K. Tolderlund ; K. Bunch-Christensen ; J. Guld
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1967
  • 卷号:36
  • 期号:5
  • 页码:759-769
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:A five-year study has shown that the tuberculin sensitivity of guinea-pigs seemingly wanes completely after BCG-vaccination over the course of years, but it can be restored by a single injection of tuberculin to the same level as that found in newly vaccinated animals of the same age. In contrast the acquired resistance to tuberculosis in guinea-pigs vaccinated several years previously is of intermediate strength, inferior to that of the newly vaccinated, and is not restored (apparently not influenced at all) by the injection of tuberculin. It is thus not possible to follow the course and eventual waning of resistance by means of repeated tuberculin testing, and the very common practice of timing revaccination of the individual according to the outcome of such testing must therefore be considered to be without scientific basis. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.1M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 759 760 761 762 763 764 765 766 767 768 769
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