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  • 标题:The specificity of tuberculin preparations obtained by chemical fractionation of unheated culture filtrates
  • 作者:Johannes Guld ; Joan Rhodes ; Ernst Sorkin
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1965
  • 卷号:33
  • 期号:3
  • 页码:385-394
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:Such tuberculin preparations as are currently used for skin testing in human beings are not specific for tuberculous infection. There is, in particular, reason to believe that the kind of low-grade tuberculin sensitivity that is highly prevalent in many tropical areas is ”non-specific”. A new kind of tuberculin, obtained as supernatant after acid precipitation followed by alcohol precipitation of the unheated concentrate from ultrafiltration of a culture of tubercle bacilli of human type, has been compared with ordinary tuberculin by skin tests in man in East Africa (Malawi) and South India. The results, reported in this paper, indicate that the new preparation gives rise to much smaller non-specific reactions than does the ordinary tuberculin. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.0M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 385 386 387 388 389 390 391 392 393 394
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