摘要：It is important for the control of vaccines to develop methods for testing their toxicity in the laboratory. Two typhoid vaccines that had given different rates of reactions among vaccinated persons in extensive field trials provided a unique opportunity for exploring the validity of the laboratory assessment of their toxicity. An elaborate design of a toxicity test based on weight changes in intraperitoneally vaccinated mice is described in this paper. The results of the laboratory test reflected the experience gained in field studies. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (780K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 673 674 675 676 677 678 679
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