摘要：This paper records an attempt to assess the prophylactic value of immune gamma-globulin, prepared from the serum of recently vaccinated adults, in the protection of close contacts of smallpox in Madras. The results serve to confirm findings of a previous study made in Madras in 1953, and show that the incidence of smallpox in close contacts given immune gamma-globulin prophylactically was about a quarter of that in the control contacts who received no such passive immunization—a statistically significant difference. Because of the limited supply of immune gamma-globulin, it is likely that its prophylactic use will be restricted to those especially at risk, for example, close unvaccinated family contacts, newborn infants and pregnant women. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (919K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 41 42 43 44 45 46 47 48
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