摘要：A mass poliomyelitis vaccination campaign, such as that under consideration in Guatemala, inevitably changes the immunological picture of a population by the artificial stimulation of antibodies in large numbers of individuals. It was therefore decided that before carrying out such a campaign, and to provide basic information for its conduct, a survey should be made to determine the degree of natural immunity to poliomyelitis and the amount of poliovirus and other enterovirus infection in the population, and to compare the poliovirus antibody titres of a small group of children who had already received Salk vaccine with those in unvaccinated children living in this area of probable high endemicity. The results of the survey show that both poliovirus and other enterovirus infections are common at an early age in Guatemala, and it is concluded that vaccination is most indicated for the 0-4-year-old group. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (926K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 255 256 257 258 259 260 261 262
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