摘要:Increased use of dieldrin for malaria control has been caused by several factors, including sporadic resistance of some vectors to DDT. Poisoning of spray-men by dieldrin has been recognized in five widely separated countries and reported informally from several others. In some cases illness has recurred months after the last exposure. Observations of antimalaria programmes in Kenya, Tanganyika, Indonesia, India (Bombay State), and Iran and a review of the relevant literature have shown that the hazard associated with dieldrin is proportional to the degree of workers' exposure as determined by concentration of spray, area of bare skin, duration of contact, and lack of hygiene. Measurements of workers' exposure and a review of toxicity by different routes incriminates skin contamination as the greatest hazard under practical conditions. It is considered that dieldrin should not be used without justification; if it is required, then certain individual and group protective measures listed in this paper may minimize, but not necessarily eliminate, the risk. The author enumerates certain features of the toxicology of dieldrin which require intensive research. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (2.3M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 891 892 893 894 895 896 897 898 899 900 901 902 903 904 905 906 907 908 909 910 911 912