摘要：The technical procedure used in the preparation of a batch of more than 500 g of purified tuberculin (PPD) is described. This batch is designated RT 23, and it is estimated that the quantity now prepared will cover the global demand for purified tuberculin for human use for several years. RT 23 has been prepared by mixing 77 smaller lots of tuberculin selected from a total of 95 lots. The method of preparing the individual lots is described and the experimental data, i.e., the yield and the biological activity ascertained by skin tests in BCG-vaccinated guinea-pigs, are given for all lots. The possible causes of variations in the yield and biological activity of the individual lots are discussed. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.2M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 829 830 831 832 833 834 835 836 837 838 839 840 841 842 843
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