摘要：The author describes an investigation, carried out in 1953-55 under the sponsorship of the Indian Council of Medical Research, to determine the relative merits of the serological tests for syphilis in current use in the major laboratories in India. Eight laboratories were included in the survey and in each the same three tests—the Wassermann test, the Kahn standard test, and the VDRL slide precipitation test—were evaluated as to specificity, sensitivity and reproducibility. In all, 921 serum samples were examined: 376 from syphilitics, 86 from patients with non-syphilitic venereal disease, 265 from patients with non-venereal diseases, and 194 from apparently normal donors. The VDRL test proved to be the most satisfactory on the average (specificity, 97.6%; sensitivity, 95.2%; reproducibility, 87.2%) and it is therefore recommended that this test be adopted as the only routine serological test in all laboratories. From the considerable inter-laboratory variations observed in the results, it is obvious that there is room for improvement in the standard of technical performance in most of the laboratories. The author suggests that by reducing the number of different tests used to a minimum, improvement and standardization of techniques would be facilitated. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (3.4M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 995 996 997 998 999 1000 1001 1002 1003 1004 1005 1006 1007 1008 1009 1010 1011 1012 1013 1014 1015 1016 1017 1018 1019 1020 1021 1022 1023 1024 1025 1026 1027 1028 1029 1030 1031 1032 1033 1034 1035 1036 1037 1038 1039 1040
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