摘要:Beginning with a discussion of the main types of toxin-antitoxin mixtures of diphtheria vaccine, the author of this article goes on to review briefly the early work done on the conversion of toxin to toxoid and the introduction of adjuvants. Among these, special attention is paid to the aluminium compounds. He also discusses the reasons advanced by different workers for the enhanced activity of vaccine under the influence of adjuvants and the difficulties met with in assessing diphtheria vaccine potency. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (657K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 473 474 475 476 477 478