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  • 标题:The “unit” in preference to the “titre” as a measure of agglutinating activity
  • 作者:N. K. Jerne
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1954
  • 卷号:10
  • 期号:6
  • 页码:937-940
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:The agglutinating activity of individual sera is usually expressed by a “titre” notation, the titre being dependent on the degree of agglutination arbitrarily chosen as the end-point. This titre may be corrected by comparison with a standard serum. A “unit” notation, however, necessarily requires both comparative measurements in relation to a standard serum and the taking into consideration of all degrees of agglutination. This involves log-dose-response curves for the standard serum and the test serum; and cases in which the distance between such curves is not constant, either at different degrees of agglutination or where different antigen suspensions are used, will bring to light fundamental limitations of the bio-assay which the simple use of titres may not reveal. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (309K), or click on a page image below to browse page by page. 937 938 939 940
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