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  • 标题:Standardization of diphtheria and tetanus toxoids
  • 作者:R. Prigge
  • 期刊名称:Bulletin of the World Health Organization
  • 印刷版ISSN:0042-9686
  • 出版年度:1953
  • 卷号:9
  • 期号:6
  • 页码:843-849
  • 语种:English
  • 出版社:World Health Organisation
  • 摘要:The author points out that determination of the mean antitoxin titre is inadequate for ascertaining fine differences in the activity of diphtheria and tetanus toxoids, but that these differences become clearly recognizable when the relation is established between the antigen dose and the proportion of individuals whose antitoxin titre exceeds a given “threshold titre” or neutralizes a given amount of toxin. Furthermore, the author states that it is not feasible to assay crude and highly purified diphtheria toxoids against the same preparation, and that two reference preparations are therefore required. Full text Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (578K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References . 843 844 845 846 847 848 849
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