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  • 标题:Antioxidant Vitamins as Oxidative Stress Markers in Rat Plasma After Physical Exercise - a Short Report
  • 作者:Agata Wawrzyniak ; Jadwiga Hamułka ; Małgorzata Drywień
  • 期刊名称:Polish Journal of Food and Nutrition Sciences
  • 印刷版ISSN:1230-0322
  • 电子版ISSN:2083-6007
  • 出版年度:2014
  • 卷号:64
  • 期号:4
  • 页码:277-281
  • DOI:10.2478/pjfns-2013-0025
  • 语种:English
  • 出版社:Walter de Gruyter GmbH
  • 摘要:The aim of the study was to verify the hypothesis that β-carotene, vitamin E, vitamin C administered individually or in combination may differently modify their levels in blood plasma being also markers of the oxidative stress. Male Wistar rats were supplemented antioxidants per os (α-to-copherol - 2 mg/d, ascorbic acid - 12 mg/d, β-carotene - 1 mg/d), both individually or in combination of 2 or 3, for 14 days. During experiment, half of the animals in each group (n=8) were subjected to treadmill exercise for 15 min at the speed of 20 m/min, to induce oxidative stress. Vitamins in rat plasma were assessed by the high-performance liquid chromatography (HPLC). Results suggest that vitamin E and C supplemented simultaneously may provide some benefit during physical exercise. The significant influence of administered α-tocopherol acetate and physical exercise on the level of α-tocopherol in the plasma was observed. Thus only the concentration of α-tocopherol in blood may be treated as a marker of oxidative stress.
  • 关键词:β-carotene ; retinol ; vitamin E ; vitamin C ; exercise ; rats
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