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  • 标题:Cultural and quality-of-life considerations when administering corticosteroids as a therapeutic strategy for African American women living with systemic lupus erythematosus
  • 本地全文:下载
  • 作者:Dorcey L Applyrs ; Edith M Williams ; Trevor D Faith
  • 期刊名称:Patient Preference and Adherence
  • 印刷版ISSN:1177-889X
  • 电子版ISSN:1177-889X
  • 出版年度:2018
  • 卷号:12
  • 页码:1007-1014
  • DOI:10.2147/PPA.S156457
  • 语种:English
  • 出版社:Dove Medical Press Ltd
  • 摘要:Objective: This study investigated the association among corticosteroids, emotional health, physical health, and work/regular activities of daily living in an ethnically diverse sample of women with systemic lupus erythematosus. Methods: A secondary analysis of data from the Medical University of South Carolina Lupus Database was conducted between confirmed cases of lupus (n = 224) and controls (n = 60). The sample comprised 57 Caucasian Americans, 141 Gullah African Americans (a subpopulation of African Americans from the Sea Islands of South Carolina and Georgia), and 86 non-Gullah African Americans. Results: Emotional health outcomes were better for women with systemic lupus erythematosus compared with controls. High emotional health scores may be influenced by cultural factors such as masking emotion, disease-coping mechanisms, religion, and strong familial and social support. Although a significant association was not detected between emotional health and work/regular activities of daily living, relationships were significant after adjusting for corticosteroid use. Conclusion: These findings suggest corticosteroid use does influence the strength of the association between emotional health and work/regular activities of daily living.
  • 关键词:systemic lupus erythematosus; emotional health; physical health; Gullah; corticosteroids; quality of life
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