期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:2018
卷号:115
期号:34
页码:E7924-E7931
DOI:10.1073/pnas.1717444115
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Crystal structures of the neurotransmitter:sodium symporter MhsT revealed occluded inward-facing states with one substrate (Trp) bound in the primary substrate (S1) site and a collapsed extracellular vestibule, which in LeuT contains the second substrate (S2) site. In n -dodecyl-β-
关键词:membrane transport ; neurotransmitter:sodium symporter ; LeuT fold ; MhsT