标题：3. THE EFFECT OF LONG TERM HIGH FRUCTOSE HIGH FAT (HFHF) DIET ON BODY WEIGHT, GLUCOSE HOMEOSTASIS AND LIPID PROFILE IN ADULT WNIN RATS by K. SIVA KESAVARAO1, T. RAGHAVA RAO2 AND P. SURYANARAYANA1#
期刊名称：Liminalities : a Journal of Performance Studies
电子版ISSN：1557-2935
出版年度：2017
卷号：89
页码：13 to 20-13 to 20
语种：English
出版社：Liminalities
其他摘要：This study was aimed at investigating the effect of high-fructose high-fat (HFHF) diet for longer duration (10 months) on body weight, glucose homeostasis and lipid profile in WNIN rats. Two months old male Wistar NIN (WNIN) rats were maintained either on AIN-93M diet alone (control group) or high fructose (32%) with high fat (24%) contains AIN- 93 diet (HFHF group) to WNIN rats developed insulin resistance associated pre-diabetes at 3 months, maintained pre-diabetes over a period of 10 months. Body weight after one month of feeding show that significantly higher in rats fed HFHF diet compared to rats fed AIN-93 diet. Rats fed HFHF diet exhibited significantly higher plasma triglycerides and significantly lowered HDL levels at the end of the experiment, but total cholesterol levels marginally reduced and LDL levels slightly higher in HFHF fed rats compared to control. These results suggest that a HFHF diet ideal for obesity and consequence of complications.KEY WORD: Effect, High Fructose High Fat (HFHF), Body weight, Glucose homeostasis, Lipid profile, WNIN rats.
